Article-Journal

Unlocking the biosynthetic potential of Paenibacilli through a genus-wide exploration of gene clusters for secondary metabolite production
ABSTRACTThe genusPaenibacillusis a prolific producer of secondary metabolites with diverse ecological and industrial applications. …
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Expanding the genome information on Bacillales for biosynthetic gene cluster discovery
This study showcases 121 new genomes of spore-forming Bacillales from strains collected globally from a variety of habitats, assembled …
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BGC Atlas: a web resource for exploring the global chemical diversity encoded in bacterial genomes
Secondary metabolites are compounds not essential for an organism’s development, but provide significant ecological and …
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A treasure trove of 1034 actinomycete genomes
Filamentous Actinobacteria, recently renamed Actinomycetia, are the most prolific source of microbial bioactive natural products. …
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BGCFlow: systematic pangenome workflow for the analysis of biosynthetic gene clusters across large genomic datasets
Genome mining is revolutionizing natural products discovery efforts. The rapid increase in available genomes demands comprehensive …
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The high mutation rate at the D614G hotspot-furin cleavage site region increases the priming efficiency of the Spike protein by furin protease: analysis of Indonesian SARS-CoV-2 G614 variants obtained during the early COVID-19 pandemic
D614G mutation plays a significant role in the transmissibility of SARS-CoV-2. Identification of other mutations related to D614G …
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UmetaFlow: an untargeted metabolomics workflow for high-throughput data processing and analysis
Metabolomics experiments generate highly complex datasets, which are time and work-intensive, sometimes even error-prone if inspected …
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Long-read metagenome-assembled genomes improve identification of novel complete biosynthetic gene clusters in a complex microbial activated sludge ecosystem
Microorganisms produce a wide variety of secondary/specialized metabolites (SMs), the majority of which are yet to be discovered. These …
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Evolutionary dynamics of SARS-CoV-2 circulating in Yogyakarta and Central Java, Indonesia: sequence analysis covering furin cleavage site (FCS) region of the spike protein
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new virus responsible for the COVID-19 pandemic. The emergence of the …
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Detection of SARS-CoV-2 spike protein D614G mutation by qPCR-HRM analysis
OBJECTIVES: Monitoring the spread of the G614 in specific locations is critical as this variant is highly transmissible and can trigger …
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